Assessment of Dolichandrone falcata Seem. Leaves for Anti-cancer Potential in Experimental Animal Models
ackground: Mammary cancer is the most common type of cancer and the leading cause of
cancer-related death in women. Despite of numerous therapeutic options, cancer remains
associated with high mortality. Traditional herb medicine has been found effective with
minimal or no side effects. Materials and Methods: The leaves of Dolichandrone falcata Seem.
(Bignoniaceae family) contains chrysin-7-rutinoside, flavanoids which possess Anti-cancer
potential. The extract obtained from Soxhlet extraction process is then assessed against the
chemical carcinogen (7,12-Dimethyl benzene anthracene) induced mammary carcinoma in rats.
Results and Conclusion: The dose dependent study and statistical comparison with the help of
graph pad prism, version 8.03 by one way ANOVA followed by Dunnett’s multiple comparison test
has revealed that the significant reduction (p
cancer-related death in women. Despite of numerous therapeutic options, cancer remains
associated with high mortality. Traditional herb medicine has been found effective with
minimal or no side effects. Materials and Methods: The leaves of Dolichandrone falcata Seem.
(Bignoniaceae family) contains chrysin-7-rutinoside, flavanoids which possess Anti-cancer
potential. The extract obtained from Soxhlet extraction process is then assessed against the
chemical carcinogen (7,12-Dimethyl benzene anthracene) induced mammary carcinoma in rats.
Results and Conclusion: The dose dependent study and statistical comparison with the help of
graph pad prism, version 8.03 by one way ANOVA followed by Dunnett’s multiple comparison test
has revealed that the significant reduction (p