Authors : Ranjana Hawaldar, Ranjana Hawaldar, Sadhna Sodani, Sadhna Sodani, Varsha Sodani, Varsha Sodani, R K. Sodani, R K. Sodani
DOI : 10.18231/j.jchm.2019.026
Volume : 6
Issue : 4
Year : 2019
Page No : 127-135
Introduction: Increase in the levels of cholesterol, triglycerides and LDL cholesterol (LDL-C) and low HDL Cholesterol (HDL-C) is known to be a risk factor for coronary artery disease (CAD) and myocardial ischaemia. Studies have shown that dyslipidemia in Indians show a unique pattern of low HDL-C, high triglycerides, and high LDL-C but such studies are few and far between. The present study was undertaken in our diagnostic centre with the aim of determining the trends in the lipid values of urban population of Indore and also to determine the gender differences in the cholesterol, HDL-C, LDL-C, Triglycerides values in the study population.
Materials and Methods: This study was carried out on a total of 5857 patients of all ages and both sexes registered in our diagnostic centre for lipid profile test on 22,23 and 24 November 2019. Dyslipidemia was defined as per the National cholesterol education programme (NCEP) and ATPIII criteria. Statistical analysis was performed on all lipid parameters and expressed as mean ± SD and median.
Results: The mean age of females was 49±12.7 years and males was 51±13.9 years with a male to female ratio of 1.34:1. The mean cholesterol value was 167.7±35.8 mg/dl and was highest in 41-50 years age group with a mean of 172.7±34.7 mg/dl.The mean triglycerides value was 140.1±79.8 mg/dl and was highest in 41-50 years of age group. The mean HDL -C was 40.5±9.7 mg/dl. Mean LDL-C was 99.3±29.5 mg/dl. The risk ratio > 4.5 was observed in 2290(39%) patients out of which 1596(47.47%) were males and 694(27.82%) were females.
Conclusion: Dyslipidemia is a major risk factor for coronary artery disease and stroke and there is an alarming increase in the incidence of CAD in younger age groups. Large scale, cross sectional, population based Studies on the pattern of dyslipidemia are needed to frame a health care policy which would be more preventive and predictive in future
Keywords: Dyslipidemia, HDL-C, LDL-C, CHD, Hypercholesterolemia, Hypertriglyceridemia.