Randomised controlled study of amniotic membrane graft versus conjunctival autograft in primary pterygium excision

Authors : Alhaj F Tasneem, Alhaj F Tasneem, Vittal I Nayak, Vittal I Nayak, Nischala Balakrishna, Nischala Balakrishna, Krithika N, Krithika N, Singri Niharika Prasad, Singri Niharika Prasad

DOI : 10.18231/j.ijooo.2020.007

Volume : 6

Issue : 1

Year : 2020

Page No : 33-41

Purpose: To study the outcome of amniotic membrane graft versus conjunctival autograft after primary
pterygium excision surgeries amongst various genders and age groups and to compare recurrences,
complications and pre and post-operative astigmatism in various grades of nasal and temporal pterygium.
Materials and Methods: A total of 90 eyes of 90 patients with previously unoperated primary pterygium
were enrolled in a randomised control trial. The patients had a follow-up of 6 months during analysis
and the results were compared retrospectively with patients who had pterygium excision surgeries with
conjunctival autografts performed by the same surgeon.
Results: A higher proportion of males underwent grafting with amniotic membrane while more females
underwent conjunctival autografting. The p value =0.011 was significant. A higher proportion of patients
were between the ages of 31-40 years and the p value=0.001 was significant. A majority of patients
from both groups had nasal pterygium with p value=0.026 being significant. The overall astigmatism pre
operatively from both groups=0.431 and 0.143 postoperatively.
Conclusion: Amniotic membrane grafting in primary pterygium surgery led to fewer complications,
recurrences and astigmatism postoperatively and was more useful in patients who may have lesser amounts
of conjunctiva for future surgeries.

Keywords: Pterygium excision, Amniotic membrane graft, Conjunctival autograft.


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