Comparitive study of effectiveness of external dacryocystorhinostomy with silicone tube placement versus silicone tube with application of Mitomycin–C in nasolacrimal duct obstruction

Authors : Neha Verma, Neha Verma, Ram Kumar, Ram Kumar

DOI : 10.18231/j.ijooo.2020.010

Volume : 6

Issue : 1

Year : 2020

Page No : 55-58

Purpose: To compare the effectiveness of external dacryocystorhinostomy(DCR) with Silicone tube(SI)
placement versus Silicone tube with application of Mitomycin–C(MMC) in Nasolacrimal Duct
Obstruction(NLDO).
Materials and Methods: The study was conducted in the department of Ophthalmology, at BRD medical
college, Gorakhpur, U.P., India between March 2018 to June 2019.It was a prospective randomized study,
where we studied 88 eyes from patients who presented with simple epiphora due to primary acquired
NLDO. The patients were randomly assigned into two groups, where one group was subjected to external
DCR along with the placement of a silicone tube ,and the other group underwent silicone tube placement
followed by the application of 0.2mg/ml of anti-metabolite MMC.
Results: After a 6 month follow-up, it was noted that there was no statistically significant difference
between the two groups, i.e., when considering patients with simple epiphora secondary to primary acquired
NLDO, external DCR with silicone tube and silicone tube with MMC(0.2mg/ml) application are at par
with each other in terms of effectiveness. However, silicone intubation with MMC is a minimally invasive
procedure when compared to external DCR with silicone tube placement.

Keywords: Nasolacrimal duct obstruction, External dacryocystorhinostomy. Mitomycin C, Silicone tube.


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