Pharmaceutical estimation of aripiprazole to assist in modern research: An upbeat review

Authors : Pritam S. Jain, Pritam S. Jain, Santosh B. Bodkhe, Santosh B. Bodkhe, Urmila R. Salunke, Urmila R. Salunke, Nitin G. Haswani, Nitin G. Haswani

DOI : 10.18231/j.ijpca.2020.001

Volume : 7

Issue : 1

Year : 2020

Page No : 1-8

Aripiprazole is second generation anti-psychotic drug. Numerous investigations that have been published previously; stating analytical methods. The reported investigations for aripiprazole in its medical preparation and biological matrices is in present report. The most widely employed approaches in analysis outlined, such as spectrometric, liquid chromatographic processes, liquid chromatography-mass spectrometry, voltammetry and gas chromatography (GC). Spectrometric methods for ARP alone and in combination are precisely stated. Which includes parameters like ? max, solvent, matrix etc. and HPLC methods for aripiprazole single and in combination are given in tabular form, to parameters like matrix, stationary phase, mobile phase composition detection wavelength etc. HPTLC methods are reported in tabular form contain parameters like mobile phase combination, stationary phase, Rf etc. LC-MS method of aripiprazole and metabolite including parameter like matrix, stationary phase, mobile phase, internal standard, flow rate, retention time etc. the statistical data regarding the utility of these methods for estimation of aripiprazole published during 2004 to 2019 is precisely presented herein assist in further analytical and formulation research in future.

Keywords: Aripiprazole, Pharmaceutical, Analytical methods, Applications, Scope, Review.


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