Status of hydroxychloroquine: COVID disease management protocol

Authors : S S Jha, S S Jha

DOI : 10.18231/j.ijirm.2020.017

Volume : 1

Issue : 1

Year : 2020

Page No : 6-10

Hydroxychloroquine, a safe derivative of chloroquine has been in practice since 1950. This drug has been used successfully as anti-viral agent previously. Its role in COVID-2 has been authenticated in the management protocol. The sudden death assigned to hydroxychloroquine is misplaced though it can be a very uncommon complication in cardiac patients with arrhythmia. Its prophylactic and therapeutic dose schedule needs to be streamlined at a lower dose schedule and is recommended to be used in early part of the disease and not during the stage of later complication.

Keywords: Hydroxychloroquine, Arrhythmia, Pathogen, Host target cell, ACE-2, Intracellular.


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