Comparative study of etomidate and fentanyl citrate with propofol (1%) and fentanyl citrate for total intravenous anaesthesia in short surgical procedures

Authors : Atikahmed Gulamdastagir Momin, Raushan Kumar Jha, Madhuri A Bhade

DOI : 10.18231/j.ijca.2020.063

Volume : 7

Issue : 2

Year : 2020

Page No : 348-354

Total intravenous anaesthesia (TIVA) is a combination of Induction agents, analgesic drugs and
muscle relaxants, excluding simultaneous administration of any inhaled drugs. This study has major
objective, to determine the efficacy of Etomidate and Propofol (1%) as anaesthetic induction agents
in termed of Induction time, maintenance doses requirements and Recovery parameters. This study
suggests that both Etomidate–Fentanyl citrate and propofol (1%)–Fentanyl citrate produced smooth
induction, easy maintenance and quick recovery with only minor hemodynamic fluctuations makes them
excellent combinations as TIVA technique. Etomidate is preferred over Propofol (1%) especially for
hemodynamically unstable patients because of minimal effects on cardiovascular and respiratory system.
hypotension and pain on injection was observed more frequently with Propofol (1%) while myoclonus with
Etomidate. With these observations in mind and careful selection of patients, both agents appear similarly
safe for use in elective and short surgical procedures.

Keywords: Fentanyl, Propofol, TIVA, Etomidate.


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