A spectrum of ocular manifestations in HIV/AIDS Patients: A retrospective analysis at a tertiary care centre in South India

Authors : S Veni Priya, S Veni Priya

DOI : 10.18231/j.ijooo.2020.027

Volume : 6

Issue : 2

Year : 2020

Page No : 129-132

Aim: To evaluate the prevalence of Ocular manifestations in HIV/AIDS patients and its correlation with
CD4 counts
Materials and Methods: The ophthalmology OPD records of 100 HIV positive patients who attended
Ophthalmology OPD(referred from ART centre in the Institute) for screening to rule out ocular
manifestations in the period of Jan 2009 to Dec 2009 were evaluated retrospectively.
Results: Out of 100 patients evaluated, ocular manifestations were seen in 54%. The percentage of patients
with Anterior segment manifestations, Posterior segment manifestations and Adnexal manifestations were
12.96 %, 31.48 % and 79.62% respectively. Conjunctivalmicrovasculopathy was the most common Ocular
manifestations seen in 36% of the patients. HIV microangiopathy was seen in 10 % of the patients and was
the most common Posterior segment manifestations. Sight threatening complications like CMV retinitis
was seen in 4 % of the patients. 60.8% of patients with ocular manifestations had CD4 count less than 100
cells/cu.mm. With the decrease in the CD4 count, the prevalence of Ocular manifestations increased. Most
common systemic association was Tuberculosis.
Conclusion: Though the prevalence of ocular manifestations is low when compared with the previous
studies, Sight threatening ocular manifestations are seen frequently in HIV patients due to increased
longevity of the patients with HAART therapy and also due to increased duration for the immune system
to mature to act against the opportunistic infections. So frequent Ophthalmic examination should be made
mandatory for all HIV patients with CD 4 count < 400> therapy.

Keywords: HIV/AIDS, HIVmicroangiopathy, CD+4 cells, OSSN, Conjunctivalmicrovasculopathy.


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