Synthesis and Anti tubercular activity of some new N’-(3-hydroxy-3, 4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid derivatives

Authors : Shripad Potadar, Ramaling Kotnal

DOI : 10.18231/j.ijpca.2020.010

Volume : 7

Issue : 2

Year : 2020

Page No : 66-68

A new series new N’-(3-hydroxy-3,4-dihydroquinoxaline-2-carbonyl)-N-phenylcarbamimidic acid
derivatives were designed and synthesized. The newly synthesized compounds were evaluated for
their anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis
and spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that;
synthesized compounds showed the good to moderate anti-tb activities.

Keywords: Quinoxaline, Orthophenylenediamine, Alloxane and antimycobacterial.


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