Metastases of malignant melanoma to stomach - An unusual presentation

Background: Malignant melanoma has been known capable of inducing metastasis in most of the human
organs. It is the most common metastatic tumor of the gastrointestinal (GI) tract; most commonly involving
the small and large bowels and rectum; however, the stomach is a rare site. Gastrointestinal (GI) metastases
are seldom diagnosed before death.
Case Presentation: Here we present a known and treated case of malignant melanoma of left foot, later
on presenting with non-specific gastric symptoms .UGIE revealed a growth in the gastric antrum for which
mucosal biopsy was performed. Histopathology revealed a poorly differentiated carcinoma and with the
help of IHC obtained a conclusion of metastatic lesion of malignant melanoma.
Conclusion: Malignant melanoma of extremities warrants a thorough endoscopic evaluation for
gastrointestinal metastases as > 60% cases are found to have lesions in stomach at autopsy. Hence an
early diagnosis of the metastatic lesions mandate for better survival of the patients.

Keywords: Malignant melanoma, Stomach metastasis.