LGGTM- A promising therapy in gastro-intestinal infections

Authors : Manish Maladkar, Ashok Yadav, Nehali Save

DOI : 10.18231/j.ijmr.2020.055

Volume : 7

Issue : 4

Year : 2020

Page No : 302-312

Probiotics are live harmless microbes which are a part of normal human gut flora, where they strive to maintain a symbiotic relationship with the human host. To date, thousands of publications exist on their functionality and their impact on prevention and treatment of various diseases. However, one of the most widely studied probiotic strain is Lactobacillus rhamnosus GG also known as LGGTM. LGGTM is extensively studied and backed by various health authorities to be effective in various gastro-intestinal tract (GIT) related diseases. Thus, LGGTM based products provide a novel approach for disease prevention and
treatment, especially in intestinal inflammatory disorders. It is well recognized that multistrain probiotic products show additional benefits by the virtue of the synergism shown when specific strains are combined. Probiotics strains selected for therapeutic use must retain their characteristics so that they deem to be efficacious for treatment of specific disease. However, in the swiftly emerging global probiotic market, end-users often have a difficult time distinguishing between high quality and poor quality products. This ambiguity impend the effective use of right probiotic strain for the right condition. This review article attempts to alert the end-users to use the right strain that guarantees the beneficial results.

Keywords: Dysbiosis, Generic probiotics, Lactobacillus rhamnosus GG, Multi- strain, Probiotics.


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