Cancer cachexia: Current strategies and future perspectives

Authors : Pranali S Kalambe, Pranali S Kalambe, Shubhada V Mangrulkarb, Shubhada V Mangrulkarb, Dhanashri T Jawald, Dhanashri T Jawald, Mayuri K Sonkusared, Mayuri K Sonkusared, Sudarshan Behered, Sudarshan Behered, Dinesh R Chaplec, Dinesh R Chaplec

DOI : 10.18231/j.ijpp.2021.004

Volume : 8

Issue : 1

Year : 2021

Page No : 17-28

Cancer cachexia is complex, and can often occur in the presence of malnutrition, age-related changes in anabolism, physical deconditioning and comorbidity. These factors can also form potentially reversible components of the overall ‘cachexia burden’. Separating cancer cachexia from the effects and complications after cancer therapy is often difficult. This review aims to briefly describe cancer cachexia and these novel biological agents currently under investigation for the treatment of cancer –related cachexia. Treatment that can be reduces the muscle wasting which is resulting into cancer cachexia. The main aim of review
is to the potential treatment for cancer cachexia, which include Pharmacological, non-pharmacological, neutraceutical and investigational new treatments.

Keywords: Cachexia, Multimodal cachexia, Mediators of cachexia.


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