Authors : Sunil Chaudhry, Sunil Chaudhry, Avisek Dutta, Avisek Dutta
DOI : 10.18231/j.ijpca.2021.004
Volume : 8
Issue : 1
Year : 2021
Page No : 19-24
The incidence of nausea or vomiting changes much with etiopathogenesis. Multiple neurohumoural pathways lead to nausea and vomiting. The various classes of antiemetics target different pro-emetic pathways to alleviate nausea and vomiting. Some drugs target more than one pathway. It is demonstrated that combination therapy is more effective than single anti-emetic agent.
Keywords: Vomiting, Chemoreceptor trigger zone, Aprepitant, Cannabinoid receptor agonist, 5 HT receptor antagonist, Neurokinin receptor antagonists.