Deciphering emesis

Authors : Sunil Chaudhry, Sunil Chaudhry, Avisek Dutta, Avisek Dutta

DOI : 10.18231/j.ijpca.2021.004

Volume : 8

Issue : 1

Year : 2021

Page No : 19-24

The incidence of nausea or vomiting changes much with etiopathogenesis. Multiple neurohumoural pathways lead to nausea and vomiting. The various classes of antiemetics target different pro-emetic pathways to alleviate nausea and vomiting. Some drugs target more than one pathway. It is demonstrated that combination therapy is more effective than single anti-emetic agent.

Keywords: Vomiting, Chemoreceptor trigger zone, Aprepitant, Cannabinoid receptor agonist, 5 HT receptor antagonist, Neurokinin receptor antagonists.


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