Malignant brenner tumor –A rare case report with immunohistochemical study

Authors : Kalaivani Selvam, Kalaivani Selvam, Banushree Chandrasekhar Srinivasamurthy, Banushree Chandrasekhar Srinivasamurthy, Sabita Pulavarthi, Sabita Pulavarthi, Ramchandra V Bhat, Ramchandra V Bhat

DOI : 10.18231/j.ijpo.2021.061

Volume : 8

Issue : 2

Year : 2021

Page No : 312-315

Background: Malignant Brenner tumor (MBT) is a rare epithelial ovarian tumor that has been not well documented in the literature. Clinical features, serum markers, and imaging studies are non-specific for the diagnosis.
Case Report: We report a case of a 76year old female who presented with complaints of bleeding per vaginum and underwent laparotomy. After an extensive sampling of the specimen, histopathological examination revealed features of malignant Brenner tumor. To support the histological diagnosis
immunohistochemical markers were done.
Result: The non-specific findings on ultrasonography were resolved with histopathological and immunohistochemical markers.
Conclusion: MBT is a rare tumor with no specific clinical or imaging findings. The application of histopathological criteria and immunohistochemistry aids in definitive diagnosis.

Keywords: Malignant brenner, Transitional epithelium, p63.


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