Authors : Suraj Mandal, Km. Shiva, K Pavan Kumar, Sweta Goel, Ramesh Kumar Patel, Shital Sharma, Renu Chaudhary, Arti Bhati, Netra Pal, Ashwani Kumar Dixit
DOI : 10.18231/j.jpbs.2021.012
Volume : 9
Issue : 2
Year : 2021
Page No : 88-94
The remarkable life structures and physiology of the eye presents huge difficulties to researchers in the field of visual medication conveyance frameworks. Nearby infusion is the most fitting and proper medication organization technique for the treatment of foremost front sickness. There are two kinds of hindrances in ophthalmic medication conveyance frameworks: static boundaries and dynamic obstructions. Static lamellae contain corneal, dermal, retinal, and retinal vessels while dynamic lamellae contain placental blood stream, conjunctiva, tear evacuation, and lymphatic seepage. These limitations influence the bioavailability of the medication. This article examines the limits of customary ophthalmic practice and the central point affecting the pharmacokinetics of the eye. Likewise, eye salves, gels, prodrugs, intranasal infusions, thickeners, entrance energizers, liposomes, microparticles, nanoparticles, visual infusions, inserts, nanoparticles, nanostructures, microemulsions, gels and periocular infusions. It guarantees the bioavailability of the medication and the controlled and constant control of the medication in the foremost and back alveoli.
Keywords: Ophthalmic drug delivery, Ocular bioavailability, Anterior and posterior segment, ODDS