Authors : Usha Ganugapati, Dominic Ong
DOI : 10.18231/j.ijpo.2022.085
Volume : 9
Issue : 4
Year : 2022
Page No : 353-356
NUT midline carcinoma (NMC) is a rare and aggressive cancer genetically characterized by a chromosomal rearrangement of the NUT gene. Primary pulmonary NMC is even more rare. NMC typically presents with histological features of a poorly differentiated squamous cell carcinoma. We report a case of a 23-year-old female patient with NMC in the lung and pleura presented to a midsize, midwestern Canadian hospital. This article emphasizes the diagnostic challenges posed by NMC and highlights an encounter with this aggressive cancer, which had not previously been diagnosed in our health region.
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Keywords: NUT, BRD4, NUT midline carcinoma (NMC)