Authors : Sanjay Choudhary, Rajiv Joshi, Dyotona Sen
DOI : 10.18231/j.ijced.2024.059
Volume : 10
Issue : 3
Year : 2024
Page No : 333-339
Localized hyperpigmented spots on the skin can cause concern due to their associated aesthetic implications. Skin types higher on the Fitzpatrick scale are particularly more susceptible to the development of hyperpigmentation. Several studies focusing on the pathophysiology of hyperpigmentation reveal that exposure to ultraviolet radiation can trigger or further exacerbate the condition. Many topical formulations are available in the market, consisting of either individual or a combination of agents. Of late, there has been an increased interest in botanical extracts as safer alternatives to traditional skin-brightening agents. However, there is a paucity of human trials evaluating the outcomes associated with such combination products.This study examined the efficacy and safety aspects related to the use of Advance Lotion, which contains , licorice, kojic acid, arbutin, and vitamin E as key ingredients, for addressing skin hyperpigmentation. The outcomes were evaluated using instrumental variables that are well-established indicators of skin pigmentation and based on self-assessment by study participants. The results revealed a significant reduction in skin pigmentation and cumulative improvements upon the continued use of Advance Lotion. There were no associated cases of skin intolerance as observed in the clinical examination or reported by the study participants. These promising results indicate the effectiveness of this product in visibly reducing pigmentation.