Autoeczematization during radiation therapy – An unforeseen crumble

Authors : Aprajita Mall, Deepti Sharma, Sudeep Marcus, Hanuman Prasad Yadav

DOI : 10.18231/j.ijmpo.2022.038

Volume : 8

Issue : 4

Year : 2022

Page No : 163-164

Radiotherapy induced acute skin reactions are common and an expected effect of radiotherapy. Radiation induced Eczematous eruptions, however, are rarely reported, with subsequent distant site eczema being infrequently seen and likely under recognized. The mechanism of autosensitization is poorly understood but seems to involve a cell-mediated immune response. Recognition is important to prevent excessive and inappropriate investigation and treatment. To the best of our knowledge and search, there are not many cases of such an autoimmune reaction to the radiation therapy. We present a unique case of eczematous reaction following 13 fractions of external beam radiotherapy in a case of non small cell carcinoma lung.

Keywords: Autoeczematization, Autosensitization, Radiotherapy, Lung cancer

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