Solitary plasmacytoma masquerading as a benign lesion

Authors : Ahna Ali Akbar, Anu Abhilash, Mayeesh Radhakrishna

DOI : 10.18231/j.jooo.2023.033

Volume : 9

Issue : 3

Year : 2023

Page No : 150-154

Plasmacytoma refers to a distinct and localized growth of plasma cells that are neoplastic and monoclonal in nature. Solitary plasmacytomas (SP) can be categorized into two groups based on their location: solitary bone plasmacytoma (SBP), which most commonly occurs in the vertebrae and secondarily in long bones, and extramedullary plasmacytoma (EMP), encompassing SPs found outside the bone. Long bones are frequently affected in solitary plasmacytomas. SBP specifically in the jaw is a rare condition, leading to challenges in diagnosis and often resulting in misdiagnosis. SBP carries a higher risk of progression to myeloma, and the primary treatment option is radiotherapy (RT). By employing RT alone, approximately 30% of SBP patients and 65% of EMP patients can achieve long-term disease-free survival (DFS). This article presents a case of a 40-year-old female patient diagnosed with solitary plasmacytoma of the mandible, with detailed documentation of clinical, radiographic, and histological features.
 

Keywords: Plasmacytoma, Multiple myeloma, Mandible.


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