Correlation of Vitamin D status with TSH levels in postmenopausal women; A pilot study

Authors : Jagroop Singh, Sukhraj Kaur, Manpreet Kaur Verma, Navneet Kaur, Manjinder Kaur

DOI : 10.18231/j.agems.2023.007

Volume : 10

Issue : 1

Year : 2023

Page No : 26-29

Introduction: Vitamin D (VitD) insufficiency is present in over half of population worldwide. Over a billion people worldwide are vitamin D deficient or insufficient. It has been long known that VitD insufficiency contributes to development of osteopenia and osteoporosis.
Materials and Methods: We performed a retrospective review of data of 60 patients in postmenopausal age group (45-75 years) during their routine blood investigation for the first time at Government Medical College and Guru Nanak Dev Hospital Amritsar over a period of 3 months (February 2023 to April 2023).
Results: Vitamin D levels were insufficient (10-30 ng/mL) in 35% of the patients, deficient (10 ng/mL) in 18.5%, and normal in the remaining 35%. TSH levels were low (less than 0.3 mIU/L) in 5%, high (more than 4.5 mIU/L) in 18.3%, and normal (0.3-4.5 mIU/L) in the remaining 76.6%. 54% (n-11) of individuals with elevated TSH had vitamin D deficiency, while 18% had insufficient vitamin D. 100%(n-3) patients with low TSH had normal vitamin D levels. TSH and vitamin D levels were normal in 22 individuals.
Conclusion: High TSH levels was associated with low vitamin D levels, low TSH levels was associated with normal serum vitamin D level. Hence association was linear between TSH and vitamin D in post-menopausal women.


Keywords: Hypothyroidism, Thyroid Autoimmunity, Hypovitaminosis D, Vitamin D Receptor


Citation Data