Authors : G. Sivakumar, R. Sathish Kumar, P. Aruna, Laksmana Perumal
DOI : 10.18231/j.ijpp.2023.024
Volume : 10
Issue : 2
Year : 2023
Page No : 116-121
Background: retained the name as Insulin plant through traditional practice, further phytochemical and pharmacological evaluation of leaves of the plant has proven record on wider therapeutic potential such as antioxidant, antimicrobial and antidiabetic activity. Our interest of current research is to explore the rhizome by multiple extraction and to screen and find out the specific therapeutic potential of the specific extracts through relevant phytochemical and pharmacological evaluation.
Methods: DPPH, Disc Diffusion and DNS methods were chosen to evaluate antioxidant and antibacterial and antidiabetic activity on various rhizome extracts (ethyl acetate, methanol, ethanol and aqueous).
Results: The anti-oxidant effect is significantly high and almost same for all rhizome extracts. ethyl acetate, ethanol, methanol has moderate antibacterial activity against gram positive ( and) and gram negative organism ( and ) by disc diffusion method as compare to the standard drug (Ceftrioxone sodium). However, aqueous extract lacs antibacterial activity. The ?-amylase inhibition activity by DNS method result infers, high antidiabetic activity for ethyl acetate and ethanolic rhizome extracts whereas mild activity for methanolic and aqueous rhizome extracts.
Conclusion: Thereby e thonolicrhizome extract might be a good choice for antioxidant, antibacterial and antidiabetic therapeutic segments among the rhizome extracts.
Keywords: AEIP – Aquous Extract of Insulin Plant, EAEIP – Ethyl Acetate Extract of Insulin Plant, EEIP - Ethanolic Extract of Insulin Plant, MEIP - Methanolic Extract of Insulin Plant.