Primary hyperoxaluria: A case report

Authors : Ankita Deshmukh, Shweta Nemade, Ramesh Kalshetty, Anitha Padmanabhan, Nitin Gadgil

DOI : 10.18231/j.ijpo.2023.041

Volume : 10

Issue : 2

Year : 2023

Page No : 195-197

Renal failure can occasionally be caused by oxalate nephropathy. Glyoxylate metabolism abnormalities and particular hepatic enzyme deficits are the causes of primary hyperoxaluria (PH). Increased intestinal absorption, an excessive diet or an increased intake of oxalate precursors can all result in secondary hyperoxaluria. A 13-month old male child with high blood creatinine, low sodium, low calcium levels, high uric acid and low urine specific gravity is the subject of this research. Medullary papillary calcification was detected using sonography (nephrocalcinosis). Calcium oxalate crystals, sparse lymphocytic infiltration and interstitial fibrosis were seen on a renal biopsy. The patient was put on peritoneal dialysis, progresses to anuria and expired due to renal failure.
 

Keywords: Calcium oxalate, Crystal, Nephropathy, Primary hyperoxaluria, Renal failure.


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