Local drug delivery with an experimental bioadhesive drug as an adjunct to scaling and root planing in chronic periodontitis – An experimental study

Authors : Pinak J Kapadia, Pinak J Kapadia, Randhir Kumar, Randhir Kumar

DOI : 10.18231/j.ijpi.2019.004

Volume : 4

Issue : 1

Year : 2019

Page No : 18-21

Introduction: The first line of treatment for chronic periodontitis has always been phase 1 therapy with scaling and root planing with oral hygiene reinforcement. Mechanical debridement may fail to eliminate pathogenic flora because of their location in areas inaccessible to periodontal instruments. Antimicrobial agents may work as adjuncts to mechanical therapy.
Materials and Methods: This study was designed as a case control study carried out on 30 patients suffering from chronic periodontitis. Two contralateral sites with moderate deep pockets in the each patient were chosen and the teeth were divided into two groups. Group A sites got scaling and root planing alone while group B sites got an adjunctive antimicrobial experimental bioadhesive drug containing tetracycline, serratiopeptidase and bactase enzyme. Recall visits were scheduled at 30 and 90 days. General linear model showed decrease in gingival and periodontal indices which was statistically significantly greater in the experimental drug group.
Conclusion: Local drug delivery with the experimental bioadhesive drug is an effective nonsurgical method for use as an adjunct to mechanical debridement.

Keywords: Mechanical therapy, Tetracycline, Local drug delivery.


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