Sclerosing epithelioid fibrosarcoma- A rare entity with a challenging presentation

Fibrosarcoma is a malignant tumour arising from fibroblasts. Several variants have been described and these prove to be a diagnostic challenge owing to its many mimics, thus often requiring ancillary testing such as immunohistochemistry. The sclerosing epithelioid variant is a poorly recognised entity that poses a therapeutic dilemma. This is a case of Fibrosarcoma-sclerosing epithelioid variant reported in a 62-year-old male who presented with an exophytic lesion on the sole of the foot and was operated for the same. This article stresses on the systematic approach to such a case which will enable the pathologist to arrive at an accurate diagnosis.
 

Keywords: Fibrosarcoma, Fibroblasts, Sclerosing epithelioid.