Steroid cell tumour of ovary: A rare clinicopathologic entity

‘Steroid cell tumors not otherwise specified (SCT-NOS)’ are rare sex cord-stromal tumors of the ovary with malignant potential, accounting for less than 0.1% of all ovarian tumors with the highest incidence in premenopausal women. These tumours represent a unique cause of female virilization. We present a case of a 48-year-old post-menopausal lady with bleeding per vagina and a 2-year history of truncal obesity and hirsutism. Past history was unremarkable. Examination revealed feature of obesity, virilization and clitoromegaly. Serum testosterone was 3.62 µg/L& CA-125 was 40.67. CECT gave the evidence of adnexal tumor, but histopathology confirmed SCT-NOS. Total abdominal hysterectomy(TAH) and bilateral salping-oophorectomy(BSO) was performed. Post-operative period was uneventful. This case is being reported for its rarity of occurrence and challenges faced in diagnosis of this case.

Keywords: Virilization, Steroid cell tumour of the ovary, Not otherwise specified (NOS).