Authors : Sadia Sultana, Nazmul Haque Robi, Riffat Rashid, Syeed Mehbub UI Kadir
DOI : 10.18231/2581-5016.2018.0026
Volume : 4
Issue : 2
Year : 0
Page No : 105-109
Introduction: Primary localized periocular and orbital amyloidosis is a very rare condition. And due to lack of suspicion diagnosis of it is often delayed. We are describing five cases of primary localized orbital and adnexal amyloidosis including the demographic data, clinical features, histopathological features and treatment outcome.
Materials and Methods: This was a retrospective study that reviewed the clinical records of five patients with adnexal and orbital amyloidosis between January 2012 and December 2016. The mean follow up time was 12 months.
Results: The series included five patients (four female and one male). The mean age was 43.6 (range: 35-55 years). Three cases had bilateral lesion and two had unilateral lesion. The average duration from the time of onset to presentation was 10.2 years (range: 7 to 15 years). The most common symptom was a mass lesion (100%), followed by irritation (40%) and ptosis (40%) and restricted ocular motility (20%). Four cases had periocular and one case had orbital involvement. The main treatment option was surgical excision.
Conclusion: Periocular and orbital amyloidosis can present in a variety of ways. A mass lesion is the most common symptom. Surgical excision resulted in good outcome. Clinical evaluation and investigation should be done in all cases to exclude systemic involvement.
Keywords: Amyloid, Orbital mass.