Authors: Akanksha Hegde*, Sindhoor, Vijaya Mysorekar
Synovial sarcoma (SS) is a rare type of high-grade soft tissue sarcoma that accounts for 5% to 10% of all soft tissue tumors. It primarily affects the soft tissue of the arms and legs. The rate of lymph node metastases in synovial sarcoma is 3% to 7%.They are locally aggressive and have a higher metastatic potential. The overall prognosis of patients is poor due to systemic metastasis. Immunohistochemistry and molecular studies are indispensable in the diagnosis of these tumors.We present to you a case of biphasic synovial sarcoma of left thigh in a 70-year-old lady with lymph node metastasis and squamous differentiation. Keywords: Biphasic synovial sarcomas, Spindle cell component, Epithelial component, Squamous differentiation, Lymph node metastasis, Immunohistochemistry, Molecular techniques.
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