Authors: Tanusri Biswas, Nabamita Chaudhury, Raston Mondal, Saswati Chattopadhyay*, Aroni Chatterjee
Introduction: Infections due to agents like , virus, virus (CMV), virus (HSV) [TORCH] are important causes of bad obstetric outcome (spontaneous abortions, still births, pre term delivery and congenital anomalies) in antenatal mothers. Such infection in adults and pregnant women are very mild or even asymptomatic but causes serious consequences in the foetus. Serological tests usually ELISA is the main mode of diagnosis. Aim: To evaluate the role of infections due to TORCH in causing pregnancy loss in BOH (bad obstetric history) mothers. Materials and Methods: A hospital based cross-sectional study was conducted to identify TORCH as a causative factor in loss of pregnancy in pregnant women with bad obstetric history attending our Antenatal OPD from March 2019 to August 2019. Enzyme Linked Immunosorbent Assay (ELISA) was done in 97 serum samples of such pregnant mothers. Results: Our observation revealed that maximum history of BOH was found in mothers aged between 26-30 years (50/97 i.e.51.55%)The IgM seropositivity was detected mostly against CMV--09/97 cases (9.28%) and abortion was found to be the commonest outcome in mothers showing IgM seropositivity to both CMV and . Conclusions: This study helps us to draw the conclusion that TORCH is an important cause of BOH and should be routinely screened. Keywords: IgM Antibody, TORCH, ELISA
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