Thirugnama S. M.

Abstract

Introduction: Neonatal seizures are significant because most of them are treatable if a specific cause is identified. Prompt diagnosis is important to plan correct treatment. The time of onset of seizures is closely related to the aetiology of seizure Objectives: The objective of the present study is to know the etiology of seizures, the time of onset, relation to the cause and the common types of seizures Methodology: 102 neonates presenting with seizures admitted in the NICU of RMH, Thanjavur Medical College, Thanjavur during January 2014 to august 2014 were taken for study, Detailed antenatal, natal and post natal history were taken and examination of baby done and HIE staged according to Modified Sarnat’s staging. Then relevant investigations were done and etiology of neonatal seizures were diagnosed and staged Results: In the present study, out of 102 neonates studied, 82 were full-term, among these 60 (58.8%) were AGA and 22 (21.6%) were SGA. 19 babies (18.6%) were preterm. Male: Female ratio in our study was 1.5:1. Conclusion: The most common etiology for neonatal seizures is HIE. Onset of seizures during first 3 days of life has significant correlation with HIE as etiology. Subtle seizures is the commonest type of seizures and is difficult to identify. Keywords: Neonatal seizures; Birth asphyxia; HIE; Subtle seizures; Hypoglycemia

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Abstract

Introduction: Rotavirus causes 40% of all hospital admissions due to diarrhea in under 5 children worldwide. Objectives: To study the incidence and clinical profile of rotaviral diarrhea and comparison of clinical, lab and demographic parameters with non rotaviral causes. Materials and Methods: Children presenting with acute diarrhea, defined as passage of 3 or more loose watery stools in under 5 years were examined for rotavirus using latex agglutination test. The incidence was calculated and the statistical difference in various clinical parameters plotted using chi square technique. Results: A total of 188 cases were enrolled for the study. 40 cases were tested positive accounting for 21%. Peak age group was 7 months to 2 years. Socioeconomically lower and middle groups, severe dehydration and hospital stay more than 4 days were more closely associated with rotaviral diarrhea. Conclusion: The incidence of rotaviral diarrhea was 21% in our study among 188 enrolled cases of acute diarrhea. Age group, severe dehydration, socioeconomic group and duration of hospital stay were significantly different in rotaviral diarrhea children. Keywords: Rotaviral diarrhea, Non-rotaviral diarrhea, Hospital stay, Dehydration.

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