Chandrika Bhut

Abstract

Introduction: It is important for parturient to have less pain and to ambulate early in order to prevent venous thrombosis and to facilitate child care. Transversusabdominis plane (TAP) block is a recent peripheral nerve block technique which is used for the lower abdominal wall surgical procedure. Materials and Methods: Study was carried out in 60 patients. Patients were randomly divided in two groups of 30 patients each by computer generated random no. method. After completion of caesarean section under spinal anesthesia, TAP block was given with 15 ml of 0.25% bupivacaine bilaterally in group Band with 15 ml of 0.25% ropivacaine bilaterally in group R. Pain severity was measured by Visual Analog Scale. Total dose and frequency of rescue analgesics required in 24 hours, effect on hemodynamic variables, side effects & complications if any were noted. Result: VAS score have significantly less in group R (PPP Conclusion: There has been growing interest in regional nerve block techniques in recent era with significant results on efficacy, as they decrease the requirement of supplemental analgesia. TAP block is a very effective technique with excellent efficacy after various abdominal surgeries including cesarean section. Keywords: TAP block, Bupivacaine, Ropivacaine.

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Abstract

The physiological changes caused by laryngoscopy and intubation are due to sympathetic discharge leads to increase in blood pressure, heart rate, oxygen consumption, leading to haemodynamic instability which may cause myocardial ischemia, left ventricular failure or cerebral hemorrhage. Aims And Objective: To assess the efficacy and safety of dexmedetomedine in attenuating haemodynamic stress response to laryngoscopy and endotracheal intubation. Materials and Methods: After institutional review board approval, 100 patients posted for planned surgery were randomized in to two groups to receive 100 ml of normal saline in Group C and Inj. dexmedetomidine 1?g/kg in 100 ml of normal saline in Group D intravenously over 10 minutes, 30 minutes before induction. Standard general anesthesia was given to all patients. Patients were monitored for haemodynamic changes and Sedation score at various specific timings as per the protocol. Result: There was significant decrease in heart rate and blood pressure after giving infusion of dexmedetomedine and remain stable during and after laryngoscopy and intubation. Conclusion: We conclude that dexmedetomidine in a dose of 1?g/kg given half an hour before induction effectively blunts the haemodynamic response to laryngoscopy and endotracheal intubation. Keywords: Hemodynamic stress response, Laryngoscopy, General anaesthesia, Dexmeditomidine.

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