Faisal Alghamdi

Abstract

Background and Objective: Mineral trioxide aggregates (MTA) is the standard material used in endodontic treatment and different dental specialties as pulp capping, repair for root perforation, retrograde filling restoration, apexification and/or revascularization. The aim of this systematic review is to assess the osteogenic activity of NeoMTA Plus in compared with ProRoot-MTA using mesenchymal stem cells. Material and Methods: Two automated databases (Google Scholar and PubMed using English-language literature) were used for this systematic review. The electronic search was done in December 2018 and updated in April 2019. Results: Our inquiry uncovered nine studies that met the exclusion and inclusion criteria. These studies investigated the osteogenic activity of NeoMTA Plus in compared with ProRoot-MTA using mesenchymal stem cells. Most of investigations in this review showed the ProRoot-MTA had a greater osteoinductivity and induced the gene expression by different MSCs exposed to it. Conclusion: Both NeoMTA Plus and ProRoot-MTA had osteogenic activity when used as endodontic repair material. Keywords: Bioactivity, NeoMTA, ProRootMTA, Mesenchymal stem cells, Osteogenic differentiation.

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Abstract

Introduction: The target of many experimental studies was to appraise the sealing ability of the root canal filling materials. No systematic reviews are available to appraise such condition. The aim of current review is to appraise the sealing ability of different root canal obturation techniques and sealers using fluid filtration method. Materials and Methods: Two automated databases (Google Scholar and PubMed using English-language literature) were used for this systematic review, using specific keywords together with inclusion & exclusion standards. In December 2018, such investigation was carried out & in March 2019, it was updated. Results: Search detected twelve studies that achieved the present inclusion and exclusion criteria. These studies illustrated different aspects of apical sealing, including: sealing ability, obturation techniques, sealer types, and updating studies in fluid filtration evaluation method. Conclusions: AH Plus had the best sealing ability over all sealers with different obturation techniques when evaluated by fluid filtration device and more investigations should be performed regarding that. Keywords: Apical sealing, Sealing ability, Obturation technique, Sealer, Fluid filtration.

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