Meerah Srinivasagam

Abstract

Introduction: Urinary tract infections (UTIs) are common in pregnancy. It is classified as Symptomatic bacteriuria & Asymptomatic bacteriuria (ASB) based on clinical presentation. Failure to detect ASB causes increased risk for Mother and fetus. Aim and Objectives: To study the prevalence, pathogens associated and antibiotic sensitivity pattern for the isolated pathogens causing significant bacteriuria among pregnant women without symptoms of urinary tract infection. Results: Out of 240 urine samples, 12(5%) showed significant bacteriuria. Prevalence of culture positivity with respect to age was maximum between the age group of 25-30 (58.33%). Prevalence of culture positivity among the trimesters, was high in the second trimester of pregnancy (75%). Among the bacteria isolated, Escherichia coli was the most (41.67%) followed by klebsiella pneumonia (25%) and CoNS (16.67%). Most of the isolates showed resistance to Cephalexin. Materials and Methods: This prospective stud y will be conducted in a Tertiary Care Hospital for a period of 1 year with 240 Urine samples of pregnant women. Conclusion: In this study, we would like to emphasize the importance of including urine culture as a routine antenatal screening test to avoid serious maternal and fetal complications. Keywords: Asymptomatic bacteriuria (ASB), Pregnant women antenatal, Significant bacteriuria, Urinary tract infections (UTIs)

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Abstract

Introduction and Objectives: CoNS which were considered as contaminants with minimal significance, have emerged as important agents of human disease. The recognition of increasing antimicrobial resistance among CoNS isolates constitutes a potentially worrisome emerging characteristic. Hence, this study was done to speciate and determine the resistant pattern of CoNS. Materials and Methods: 122 clinically significant CoNS isolates were obtained from various clinical samples between August 2016 to July 2017. These samples were processed conventionally. Results: Of the 122 CoNS species isolated majority were from pus. Identification of CoNS showed S.epidermidis 70 (57.4%), as the most frequently isolated species. Antimicrobial susceptibility pattern of the isolates showed maximum resistance to Penicillin. Methicillin resistance was seen among 19 (15.6 %) isolates. But all the isolates showed 100% sensitivity to glycopeptides and Linezolid. Conclusion: Meticulous identification, speciation and resistant pattern of the isolate is of paramount importance in clinical management of patients. Keywords: Coagulase negative Staphylococci(CoNS), Contaminant, Anti microbial susceptibility pattern, Methicillin resistance

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