Juveria Jahangir

Abstract

Introduction: Wound infection is a common problem in obstetric and surgical procedures. It is not clear whether perioperative prophylaxis of one portion of anti-infective agents is sufficient to prevent wound contamination. This test was aimed at assessing whether anti-infection of one perioperative part was successful in counteracting diseases after use in women undergoing caesarean section. Materials and Methods: This is a multicentre study. Participants were given a single dose of 1 g of cefotaxime intravenously before surgery, and the incidence of postoperative complications such as wound infections, wound resuturing, etc. was monitored. Results: The study included 100 elective caesarean sections. Cefotaxime injection of 1 g IV was injected 30 minutes before surgery. The incidence of febrile morbidity was seen in 10 %, and wound infection was in 5% of total patient. The microorganisms isolated from the wound infection were E. coli, Pseudomonas, which were sensitive to cefoperazone-sulbactum and linezolid. The average length of hospital stay was 4 days. Conclusion: A single prophylactic dose of cefotaxime is effective for the prevention of postoperative infection. The results obtained in this study shows that single-dose antibiotic prophylaxis is effective. The resistance of microorganisms can be prevented with this prophylactic single-dose antibiotic. This prospective study confirms that one-time antibiotic prophylaxis had a positive effect on women undergoing a planned caesarean section. Keywords: Elective cesarean section, Single dose of antibiotic, Prevention, Wound infection.

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