Kinal Shah

Abstract

Objective: Dengue virus is the most common arbo virus found in India. Our study has conducted to study the epidemiological and demographic characteristic of dengue fever during the year 2017 in Ahmedabad region of Gujarat state India. Materials and Methods: A retrospective study was performed at the Department of Microbiology, Dr. M.K.Shah Medical College and research centre and smt. S.M.S. multispeciality hospital Ahmedabad, Gujarat from July 2017 to October 2017. A total of 611 blood samples were collected during the study period and serologically tested for dengue NS1 antigen and IgM antibody by capture ELISA testing. Patient with clinically suspected dengue and found positive for dengue NS1 antigen and/or dengue IgM Ab was considered as a case. The data was entered in software and analyzed. Results: We have tested 611 serum samples for dengue infection during the study period in our hospital. Out of which 104(17%) serum samples were positive for dengue infection. 77 serum samples were positive for Dengue NS1 antigen ELISA and 27 serum samples are positive for Dengue IgM ELISA. Majority of samples were tested positive in age group 14-25 year (64.5%) and 26-60 year (32.7%). It shows prevalence of dengue infection is more in male (82.7%) than female (17.3%). Conclusion: Rapid urbanization in developing countries increases prevalence of dengue. Virus activity is high during monsoon and post monsoon period which co-insides with increase vector breeding. Effective implementation of vector control measures through efforts toward vector breeding source reduction help in reduction of the dengue prevalence in community. Keywords: Dengue, NS1 antigen, IgM antibody, Seroprevalence.

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Abstract

Objective: C-reactive protein, total White Blood Cell count and Absolute Neutrophil counts are important inflammatory markers. These tests are highly significant as predictor of bacterial infection in febrile children. Materials and Methods: We have collected data of 149 samples from pediatric indoor and outdoor patients. Samples were collected in both plain and EDTA vacuette. From plain vacuette CRP test was done and from EDTA vacuette total WBC count and absolute neutrophil count were done. Results: In present study we have collected data of 149 pediatric patient. Total number of patient having bacterial infection were 101. Out of which CRP positive samples were 91(90%), 56(55.4%) samples show leucocytosis and 36(35.6%) samples show neutrophilia. Conclusion: CRP test along with total WBC count and Absolute Neutrophil Count will be helpful for early prediction of bacterial infection and this test will guide clinician for better outcome of febrile children. Keywords: C-reactive protein, Total WBC count, Absolute Neutrophil count, Bacterial infection, Children.

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