Amrish Kohli

Abstract

Pseudomonas aeruginosa has established itself as an important pathogen because of its ability to survive the hostile environments and causing life threatening infections. This gram negative bacillus has acquired resistance to different classes of antimicrobials thereby increasing the morbidity and mortality. In the present study we aim to analyze the rate of isolation of this opportunistic pathogen from various body fluids as well as respiratory and pus samples and the antimicrobial resistance profile of all these isolates. Standard microbiological techniques were used for its isolation, culture and identification followed by the antimicrobial sensitivity testing using disk diffusion method. Of the 3530 samples received over a two year period, the presence of Pseudomonas aeruginosa was detected in 71 samples (9.16%). A higher resistance was observed for ceftriaxone, ceftazidime and ciprofloxacin but a considerable number of isolates were sensitive to carbapenems. Most of the isolates were sensitive to polymyxin B. Keywords: Pseudomonas aeruginosa, Multidrug resistant (MDR), Extensively drug resistant (XDR), Outpatient department (OPD), Inpatient department (IPD).

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Abstract

Introduction: Staphylococcus aureus is a virulent pathogen in humans capable of surviving in the hospital environment as a saprophyte and in the human body as a normal commensal. It is a gram positive cocci which is capable of causing serious and life threatening infections like bacteremia and pneumonia with high morbidity and mortality. Presence in the blood increases its chances of metastasis and the risk of fatality. The choice of antibiotic therapy has conventionally relied to a large extent on the susceptibility of the pathogen to methicillin. In our study we intend to analyze the cases of different infections caused by Staphylococcus aureus both from the community and hospital environment with main focus on methicillin resistant strains. Keywords: Methicillin resistant Staphylococcus aureus (MRSA), Methicillin susceptible Staphylococcus aureus (MSSA), Hospital acquired Methicillin resistant Staphylococcus aureus (HAMRSA), Community acquired Methicillin resistant Staphylococcus aureus (CAMRSA), Out-patient department (OPD), In-patient department (IPD).

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