Authors: Poornakala S, Richa Bhartiya, Nina Desai, Neha Pokharna
Amyloidosis is a rare systemic disease characterised by deposition of misfolded aberrant precursor protein, which forms fibrils in beta-pleated sheets. Waldenstrom’s macroglobulinemiais one of the uncommon causes of systemic amyloidosis. Diagnosis of systemic amyloidosis in Waldenstrom’s Macroglobulinemia is crucial, as it is one of the indications of treatment. Biomarkers play major role in early detection of amyloidosis, which is managed by treatment of underlying plasma cell neoplasm with rapidly acting agents. Here we are presenting a case of 73-year-old male, a case systemic amyloidosis with underlying Waldenstrom’s Macroglobulinemia. Keywords: Amyloidosis, Lymphoplasmacytic lymphoma, Plasma cell neoplasm, Abdominal fat biopsy, Biomarkers.
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