Smita A Sawant

Abstract

Phyllodes tumors are uncommon fibroepithelial tumors of breast that have potential for recurrence and metastasis. Triple assessment by clinical, radiological and histological examination forms the fundamental basis for the evaluation of phyllodes tumor. Treatment could be either by wide excision or mastectomy provided that clear histological margins are achieved. Wide local excision with at least 1 cm clear margin is currently the standard of treatment of phyllodes tumor in most institutions. Most of these behave in benign fashion however, malignant tumors have higher tendency for local recurrence and systemic dissemination to lungs, brain. Lymph node involvement is rare. Keywords: Phyllodes tumor, Malignant, Metastases, Lymph node.

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Abstract

Acquired perforating collagenosis, is a rare itchy, debilitating cutaneous disorder usually associated with diabetius mellitius and renal failure or both. The diagnosis is usually based on skin biopsy. The objective of our study is to review and co-relate the clinical and pathological features in acquired perforating. We present ten cases of histopathologically proven acquired perforating collagenosis, associated predominantly with diabetes mellitus. Seven out of ten patients had history of diabetes mellitus for more than ten years. Thyroid disorders were seen in three patients along with diabetes mellitus. Two had no underlying systemic diseases. Clinically skin eruptions were multiple, pruritic papules and nodules with central crust formation, located primarily on lower extremities and occasionally on back. Keywords: Acquired perforating dermatosis, Diabetes mellitus, Chronic renal failure.

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