Authors: Tahir Husain Ansari, Yusuf Rizvi
Background: VKC is of great concern to all ophthalmologists in India because it is found to be quite common in our country and the tropical countries and if untreated it can lead to sight threatening complications. Materials and Methods: The present study was carried out in fourty patients who attended the outpatient department ophthalmology, Darbhanga Medical College and Hospital, Laheriasarai. The study was carried out from July 2007 Dec 2008. Forty patients with symptoms of VKC (ocular itching, ropy discharge discharge, papillary hypertrophy, gelatinous thickening and (horner-trantas spots) were selected and included in our study. Results: Olopatadine treated group- Means score of itching at 0, 14, 28, 42 days in olopatadine treated eye were 3.2, 2.1, 1.2, and 0.4 respectively having value P score at same stages in Placebo eye were 3.2, 3.1, 3 and 2.6 having p value >0.05. Olopatadine Treated Group-Mean scores of ropy discharge at 0, 14, 28, and 42 days in were 2.9, 2.1, 1.3 and 0.6 respectively having P value eye were 2.9, 2.8, 2.7 and 2.4 respectively having P value >0.05. Conclusion: It was concluded that the present study shown that both olopatadine and epinastine is effective and reducing itching and ropy discharge of VKC as compared to placebo. Keywords: Epinastine hydrochlloride, Itching, Olopatadine hydrochloride, Placebo, Vernal keratoconjuntivitis, Ropy discharge.
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