Authors: Shubhangi T Shevale, G V Narendra, K Srinivasa Rao, V S Gurunadh
Purpose: Study aims to establish the efficacy and safety of intravitreal triamcinolone injections in the denovo treatment of DME in a rural poor socio-economic set up. Materials and Methods: 4 mg Intravitreal injections of 04 mg of triamcinolone acetonide (IVTA) was given to 50 DME patients as an initial treatment. Best corrected visual acuity (BCVA), central retinal thickness (CMT) and intraocular pressure (IOP) were analysed before and after the treatment at intervals of 1 week, 1 month, 3 months and 6 months. Result: Statistically significant improvements were observed in BCVA, as well as a decrease in CMT after all time-intervals following IVTA. IOP increases were observed 1 week, 1 and 3 months after IVTA, but not at 6 months after IVTA. No sight-threatening side effects of IVTA were observed. Conclusion: IVTA is effective therapeutic measure in control of DME; it could be a therapeutic option of choice in patients with poor socioeconomic status. Keywords: Best corrected visual acuity (BCVA), Diabetes mellitus (DM), Diabetic macular oedema (DME), Intravitreal triamcinolone acetonide (IVTA).
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