Sriya Sridhar

Abstract

Purpose: To report the frequency of corneal dystrophies. Materials and Methods: All patients who presented to the out-patient department were examined for signs of corneal dystrophy from January 2017 to December 2019. All patients underwent a thorough evaluation for demographics, clinical presentation, history of consanguinity, family medical history, and clinical outcome of keratoplasty (in those who required it) and a clinicopathologic correlation was attempted. Complete ophthalmological examination was conducted for all patients which included vision (distance & near), slit lamp examination, retinoscopy, auto refractometer readings, dilated fundus examination, pentacam as well as anterior segment OCT. Photographic documentation was done for all dystrophy patients. Results: During this time period we had 118 patients who were included in the study. History of consanguineous marriage was noted in 62% of the study population. History of a similar problem in siblings and other members was elicited in 27 (22.88%) and 15 (12.71%) patients, respectively. 23 patients required keratoplasty. The average follow-up of each keratoplasty case was 3614 months. Among these cases, only 2 groups had graft failure, viz, CHED and macular dystrophy. Conclusion: The higher frequency of dystrophies could be due to higher consanguineous marriage, which indicates a need for counselling. Also, there is an increased need for thorough work-up before planning intraocular procedures. Keywords: Corneal dystrophy, Endothelial, Keratoplasty, Stromal.

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Abstract

Introduction: To compare various accommodative parameters in peri-presbyopic diabetic patients with age-matched healthy individuals. Aim: To compare Four Accommodative parameters in peri-presbyopic early onset diabetic patients and age matched non-diabetic individuals. Objectives: 1. To compare and analyse Four accommodative parameters in peri-presbyopic early onset diabetics with that of peri-presbyopic age matched non-diabetic individuals (35-45; years); 2. To analyse the effect of treatment / metabolic control on the parameters. 3. To observe, if any, other systemic association that affects accomodation in both cases and controls. Materials and Methods: Study setting – peri-presbyopic symptomatic patients attending the Ophthalmology outpatient department, from August 2016- December 2016. This cross-sectional casecontrol study was performed on 50 young onset peri-presbyopic early onset symptomatic diabetics and 50 age-matched peri-presbyopic, Non-diabetic individuals. Using the best correction for distance visual acuity, multiple accommodative ability tests such as near point of accommodation, accommodative amplitude, negative or positive accommodative facility and near point of convergence were measured in both groups. Results: Statistical analysis made using SPSS version 16 Normality of distribution was checked with Kolmogrov-Smirnov test. Differences in accommodative functions between groups tested using student T test, Man Whitney test and repeated measures of analysis of variances. Level of significance was set at p-values Mean positive RA, Mean negative RA and Mean NPC did not reach statistical significance. Conclusion: Majority of accommodative ability functions are decreased in Peri-presbyopic diabetic patients. Early detection and rehabilitation of such patients with full near vision correction is strongly recommended. Keywords: Accommodation, Convergence, Early onset diabetics, Peripresbyopic patients.

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