Rajeev Saxena

Abstract

Osseous metaplasia in a leiomyoma is an uncommon clinical entity with the presence of mature and immature bone in a leiomyoma. Infection, necrosis, hyaline degeneration, calcification and myxoid degeneration are the most common secondary degenerative changes seen in cases of leiomyoma. Calcified and ossified leiomyomas are uncommon and is rarely reported in literature. We report one such case in a 45 year old perimenopausal female who presented clinically with abnormal uterine bleeding. Multiple nodules were seen in bilateral broad ligaments, which on histopathology revealed features of osseous metaplasia in hyalinized degenerated leiomyomas, an extremely rare clinical entity.   Keywords: Leiomyoma, Metaplasia, Osseous

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Abstract

Fine needle aspiration is the mainstay in the diagnosis of Lymphadenopathies. In present study the purulent aspirates from lymph nodes were evaluated for etiological agents to know the distribution pattern of various disease agents. Materials and Methods: This study was a prospective one covering 100 cases taken from patients attending MBS and NMCH Hospitals under Govt. medical college, Kota. Our study spanned from January to December, 2017. Results and Conclusion: Out of a total of 100 cases incidence of different types of lymphadenopathies were, Tubercular, 55%, Acute suppurative, 27%, Granulomatous Inflammatory, 12% and Metastatic Carcinoma, 6%. Cases of lymphadenopathy showed a wide age range from 1 to 73 years. Male to female ratio was 1:1.04. AFB positivity was seen in 61.8% cases of Tubercular lymphnoditis. Among the 55 cases of tubercular lymphnoditis, 46 (83.6%) cases showed Auramine Rhodamine positivity while only 34 (61.8%) corresponding cases were positive by Ziehl Neelsen stain, demonstrating higher sensitivity of Auramine Rhodamine stain. In present study, commonest cause of Metastasis in lymph nodes was Squamous Cell Carcinoma (33.3%). Other diagnosis were Metastatic Adenocarcinoma, Duct carcinoma breast, Mucoepidermoid carcinoma and poorly differentiated carcinoma. On gram’s staining out of 27 cases of Acute suppurative lymphnoditis, 3 showed positivity for gram positive cocci. Out of 3 cases, 1 case showed gram positive cocci in clusters and 2 cases showed gram positive diplococci. Diplococci were more common in younger population. FNAC is a safe, convenient, rapid and inexpensive first approach procedure, without any complications in evaluation of cases of lymphadenopathy and can be practiced even in peripheral hospitals where histopathological techniques are not available. Keywords: Lymphadenopathy, FNAC, ZN stain, Granulomas.

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Abstract

Lesions of the salivary glands present an interesting subject matter because of their great histologic diversification. This study was carried out to study the histopathological spectrum of salivary gland lesions and to know their pattern of distribution. The study was done with available data from January 2015 to December 2017 in the Dept. of Pathology, Govt. medical college, Kota. Aims and Objectives: Out of a total of 138 cases, 75(54%) were neoplastic and 63(46%) were non neoplastic. Male predominence was observed with a M: F ratio of 1.5:1. The mean age observed was 46.7 years in a age range of 12 to 75 years. Benign tumors outnumbered the malignant ones. Parotid gland was the most common site of tumors (73.5%) and Pleomorphic adenoma was the commonest tumor observed in both sexes. Muco-epidermoid carcinoma was the most common malignant salivary gland tumor, followed by adenoid cystic carcinoma and squamous cell carcinoma. Owing to the complex features exhibited by salivary gland lesions histopathological examination is the mainstay for diagnosis and categorization. Keywords: Histopathology, Salivary gland, Pleomorphic adenoma, Mucoepidermoid carcinoma.

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