Sheba S K Jacob

Abstract

A 51-year-old gentleman developed a rapidly progressing inguinal mass three months post corona virus disease (covid-19) infection. On examination, there was generalized lymphadenopathy confirmed by CT scans and a lymphoma was suspected. On light microscopy there were features of Rosai Dorfman disease with associated necrotizing granulomas amidst the large cells in the sinusoids, which have not been described before in Rosai Dorfman disease. Gene x-pert for tuberculosis, bacterial, fungal and acid fast bacilli cultures were negative. We present this case report for documenting this presentation post COVID-19 infection with review of literature.   Keywords: COVID­19, Rosai Dorfman disease, Hemophagocytosis

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Abstract

Background: This is the first case report of a mucinous cystadenoma of the thymus. So this case is reported for awareness that mucinous cystadenomas can occur in the mediastinum with a review of literature and the need for complete surgical excision. Case Report: A twelve year old girl with a cystic mediastinal mass, presented with dry cough for three weeks. The mass was completely excised as it was huge and causing pressure symptoms. On light microscopy, there was thymic tissue with a mucinous cystadenoma. This is the first report of a mucinous cystadenoma in the thymus. Mucinous cystadenomas can grow into large sizes and become symptomatic due to pressure or rupture prompting investigation. Conclusion: Complete surgical excision is advised as mucinous cystadenocarcinoma of the thymus has to be ruled out by adequate sampling and careful analysis of the morphology.   Keywords: Mucinous cystadenoma, Thymus, Mediastinal mass, Child

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