Authors : Jegan C, Jegan C, Mangayarkarasi V, Mangayarkarasi V, Rukadikar AR, Rukadikar AR, Anandi V, Anandi V
DOI : 10.18231/2394-5478.2019.0002
Volume : 6
Issue : 1
Year : 2019
Page No : 6-10
Introduction: Bacteraemia means presence of microorganisms in circulating blood or blood stream. Septicaemia means multiplication of microorganisms and production of toxins in blood stream. Bacteraemia may be transient, intermittent or continuous. The two categories of blood stream infections are intra vascular and extra vascular. Early microbiological diagnosis and determination of antimicrobial sensitivity pattern have been shown to improve treatment outcome.
Aim: To isolate the causative agents and determine the antimicrobial sensitivity pattern from the blood sample of patients with bacteraemia/septicaemia.
Materials and Methods: Hospital based prospective cross sectional study conducted at SRM Medical College Hospital and Research Centre, Potheri, Kancheepuram District. Total 765 blood sample were collected during March 2012 to February 2013 from bacteraemia diagnosed cases. The blood samples were collected and processed by standard methods. Isolation and identification of organisms was done as per standard guidelines. Antimicrobial sensitivity was determined by Kirby Bauer’s Disc diffusion method as per CLSI guidelines.
Observation and Result: Among 765, 416 (54.37%) were male and 349 (45.62%) were female. Among the total sample of 765, 114 (14.9%) showed positive. Present study showed predominance of Gram positive organisms i.e. 60 (52.66%) over Gram negative organisms, i.e. 51 (44.73%) and 3 (2.63%) Fungal isolates.
Conclusion: Timely detection and appropriate treatment will help to reduce the morbidity and mortality of patients. Also, such studies will helps in developing guidelines and antibiotic policy for better outcome of the patients.
Keywords: Bacteraemia, Antimicrobial sensitivity testing.