Authors : B Neeharika, R Vinod, Gerard Rakesh
DOI : 10.18231/j.ijmr.2019.074
Volume : 6
Issue : 4
Year : 2019
Page No : 350-354
Introduction: Chronic osteomyelitis is a important medical illness among developing countries, it is a very
expensive disease for the patient and society mostly associated with trauma and surgery as risk factors.
There is a constant change in the trend of organisms involved and resistance pattern seen with advent of
newer antibiotics, So early and specific therapy is needed. With this background present study aims to look
for the varying trends of microorganisms involved in osteomyelitis and their antimicrobial susceptibility
pattern.
Materials and Methods: A total of 100 cases studied over a period of one year, samples processed by
following standard laboratory protocols and along with routine antimicrobial testing screening for MRSA
done.
Results: Among 100 cases, 76 were males and 24 were females, between age group of 11 –60
years. Long bones are most involved with trauma (45%) as risk factor. Staphylococcus aureus (51%)
predominant pathogen isolated with 27(53%) were MRSA, followed by Pseudomonas aeruginosa (16%).
Antibiotic sensitivity testing of gram positive organisms showed hundred percent sensitivity to Linezolid
and Vancomycin with poor sensitivity to Pencillin (10/15.6%). Among gram negative organisms,
majority showed highest sensitivity to Amikacin (73.3%) & Imipenem (71.1%) with poor sensitivity to
Ciprofloxacin (20.0%) and Ampicillin (0%).
Conclusion: Chronic osteomyelitis is a prime challenging problem in many countries with severe
morbidity. Mostly due to neglect, delayed or inadequate treatment and emerging drug resistant pathogens
involved. Culture based antibiotic therapy helps in effectively treating the disease also prevents the drug
resistance.
Keywords: Chronic osteomyelitis, MRSA, Staphylococcus aureus.