Authors : Nidhi Vala, C Shrinivasan
DOI : 10.18231/j.ijpo.2019.103
Volume : 6
Issue : 4
Year : 2019
Page No : 530-533
Introduction: Bone marrow examination becomes a crucial test in diagnosis of both hematological and non
hematological malignancies, when the routine peripheral blood and other laboratory tests are not conclusive
of a diagnosis.
Aim: The aim of this study was to find the indications of bone marrow and to assess the diagnostic value.
Materials and Methods: A total of 160 cases were analyzed retrospectively from January 2016 to
December 2017. All the bone marrows received at the laboratory were included in the study.
Result: The youngest patient was 2 years old and the oldest 80 years. Amongst 160 cases 89
(55.62%) were male and 71 (44.37%) were female. M: F ratio is 1.25:1. Leucocytosis was the most
common indication of bone marrow examination followed by bicytopenia and pancytopenia. Acute
leukemia was the most frequented diagnosis (13.12%) followed by idiopathic thrombocytopenic purpura
(11.25%), myeloproliferative diseases (8.12%) and myeloma (8.12%). Few of the rare diagnosis included
hemophagocytic syndrome, hypersplenism and aplastic anemia.
Conclusion: The study concludes the bone marrow examination is crucial and important in reaching a
diagnosis in most of the cryptic cases of cytopenias and unexplained leucocytosis.
Keywords: Bone marrow examination, Cytopenia, Leukemia