Pattern of congenital anomalies and associated maternal risk factors : A study from Mysore, South India

Authors : Mamatha Shivanagappa, Swathi Hassan Kumarachar, Mahesh Mahadevaiah, Madhumitha Mahesh

DOI : 10.18231/j.ijogr.2019.097

Volume : 6

Issue : 4

Year : 2019

Page No : 444-447

Introduction: Morphlogical abnormalities arising due to structural defects or abnormal formation of
tissues or organs are known as Congenital malformations. Most of the malformations have mixed genetic
and environmental causation. Incidence of congenital anomalies differs from country to country and
from region to region within same country. This study aimed to the study maternal risk factors and their
association with pattern of congenital anomalies in a tertiary care hospital of South India.
Materials and Methods: This was a retrospective study. Data from case records of mothers admitted
with congenital anamolies in the fetuses were reviewed and analysed. The case records were from the
department of Obstetrics and Gynecology, JSS Hospital over a two year study period. There were 47
mothers who had given birth to anamalous fetus and their details were studied with respect to risk factors
involved and the pattern of congenital anamalies.
Results: The maternal risk factors such as history of previous abortions(27.7%), consanguinity (10.6%),
rh-negative pregnancy (6.4%)and anomalous uterus (6.4%) were the most significant factors identified.
Congenital anomalies were mostly found to be involving central nervous system(74.5%), musculoskeletal
system (29.8%) and cardiovascular system(12.6%).
Conclusions: Major maternal risk factor identified among the study group was history of previous
abortions. Incidence of anamolies were most involving central nervous system and musculoskeletal system.

Keywords: Fetal Development, Embryogenesis, Neonatal Mortality, Congenital Malformations.

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