Authors : Chilamakuru Raghavendra, Chilamakuru Raghavendra, G Ram Kumar Gupta, G Ram Kumar Gupta, V Venkata Ramana Reddy, V Venkata Ramana Reddy
DOI : 10.18231/j.ijirm.2019.047
Volume : 4
Issue : 4
Year : 2019
Page No : 205-209
Introduction: Lung is one of the commonest sites for neoplasms both primary and metastatic cancers.
Identification and determination of histopathological play a major role in the diagnosis and treatment of
cancer. Radiology and imaging helps in the selection of procedures to obtain a tissue sample for the
diagnosis and management of lung cancer. The present study was aimed to analyze the clinic-pathological
profile of primary lung cancer in the south-east coast of India.
Materials and Methods: A prospective, observational study was conducted in the Department of
Pulmonary Medicine, Maharaja Institute of Medical Sciences (MIMS), Vizianagaram, Andhra Pradesh,
India. A total of 104 patients with primary lung cancer were enrolled. Radiological, clinico pathological
profile and Histopathological analysis was done individually for all patients.
Results: Male patients (70.1%) were more compared to females (29.9%). The Average age of the study
population was 57.8 years. A total of 70(67.3%) study subjects had a history of smoking comprising of 61
males and 9 female subjects. Almost all study patients had clinical presentations of cough and shortness of
breath (100%). Most common X-ray and CT chest radiographic feature was mass lesion (n=89 and n=91).
Adenocarcinoma was identified in 79 patients (76.0%) as the most common histological type and it was
also common in both smokers (n=49) and nonsmokers (n=29).
Conclusions: The most common histological variant was Adenocarcinoma followed by squamous cell
carcinoma. Among men, smoking is the principal risk factor in the causation of lung cancer. A precise,
accurate and rapid screening method is still warranted for the diagnosis of primary lung cancer.
Keywords: Adenocarcinoma, Bronchoscopy, Clinico-pathological profile, Histopathological profile, Primary lung cancer.