Aetiopahogenesis and management of chronic urticaria -A Study

Authors : Rashmi Rani, Dharmendra Kumar

DOI : 10.18231/j.ijced.2019.057

Volume : 5

Issue : 4

Year : 2019

Page No : 264-270

Introduction: Urticaria more commonly known as “ Nettle rash ” or hives, presents as circumscribed,
raised (oedematous), usually pruritic evanescent skin lesions. The lesions may be pink or red, although
classifiably they are pale wheals surrounded by an erythematous flare. Approximately 15% to 20% of the
general population will have urticaria at least once during their lifetime. Persons of any age may experience
urticaria and/or angioedema.
Materials and Methods: 150 cases of chronic urticaria of both sexes and of different age group were
selected from the out patient department of Dermatology, Narayan medical college Sasaram Bihar. Cases
having more than 6 weeks of duration of disease were included in the study.
Result: The maximum no of cases were seen in the age group of 25-34 years (34.6%), in 35-44 years no
cases are 25.4%, 21.4% in age group 15-24 yrs and 18.6% in age group 45-55. duration of chronic urticaria
ranging from 6 weeks to 24 months. Maximum numbers of cases (66.67%) were having duration up to 12
months. Only 33.33% were having duration more than 12 months
Discussion and Conclusion: Maximum number of patients presented with the duration of disease of 12
Finding suggest association of cyst of Amoeba and Giardia in some cases. Raised serum TSH and IgE level
was seen in some cases. Non veg diet especially fish was associated with Chronic Urticaria.
Antihistamines are the most effective and preferred drug for the treatment of Chronic Urticaria.Traditional
antihistaminic (hydroxyzine) and second generation antihistamines (levocetrizine and fexofenadine) was
prescribed in therapeutic dosages and there results were interpreted.

Keywords: Urticaria, Management, Aetiopathogenesis.

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