Authors : Nutanbala N. Goswami, Jignesh Gondliya, Alpeshpuri P. Goswami
DOI : 10.18231/j.ijcaap.2019.027
Volume : 4
Issue : 4
Year : 2019
Page No : 131-133
Introduction/Aim of study: Use of some antipsychotic agents results in haematological changes like leukopenia, neutropenia, thrombocytopenia, anaemia, Leukocytosis, thrombocytosis which may present a major problem for the management of psychotic patients.
Material and Methods: Twenty four patients on therapy with antipsychotic drugs for a minimum period of three months were recruited for study for haematological changes at tertiary care Hospital of India. The study was conducted between March and august, 2019.
Results: Out of 24 cases, 1 patient developed neutropenia (4.16%), and 01 patient developed anaemia (4.16%) within 3 month of treatment without any haematological disease.
Conclusion: The significant reduction in blood cell count observed associated with antipsychotic agents especially neutropenia. An appropriate monitoring strategy should be used for clozapine and other antipsychotic drug to minimize the adverse drug reaction and early shift of treatment.
Keywords: Antipsychotic drugs, Haematological parameters, Neutropenia.