A quasi interventional study on the efficacy of long pulsed Nd:YAG laser (LPND) in the treatment of periorbital wrinkles in a tertiary care hospital

Authors : Madhuri B, Spandana P Hegde, Manjunath Shenoy M, Vishal B, Malcolm Pinto

DOI : 10.18231/j.ijced.2020.011

Volume : 6

Issue : 1

Year : 2020

Page No : 45-49

Introduction: Wrinkles or rhytids are a part of the natural ageing process of the human body. Long pulsed
Nd: YAG laser (LPND) promotes dermal collagen remodelling without damaging the superficial layers and
hence reduce periorbital wrinkles.
Materials and Methods: Patients seeking treatment for periorbital wrinkles, and willing to participate in
the study were included. Wrinkles were graded on the basis of wrinkle severity score (WSS) at baseline
and one month after 4 monthly sessions of treatment. The 1064nm LPND was employed with settings of:
spot size - 10mm, on time - 40 to 50 ms, fluence - 30 to 50 J/cm2 and frequency - 1 Hz. Three overlapping
passes were done on both sides of the face. Outcome was measured by subjects, investigator and a blinded
dermatologist. Appropriate statistical analysis was done.
Results: Twenty eight sites were treated in 14 subjects. Male to female ratio was 3:4. Their mean age was
45.86 8.75. Mean WSS by investigator at baseline was 3.18 1.188 and at the end of treatment was 1.89
1.031 (p = 0.001). Mean WSS by the blinded dermatologist was 3.18 1.188 at baseline and 2.43
1.034 at end of the treatment (p =0.001). The subject’s degree of satisfaction was found to be 2.96 1.036.
There were no significant adverse events.
Conclusion: LPND for periorbital wrinkles is both patient and physician friendly, offering maximum
results with minimal discomfort and downtime. This modality needs further exploration in the treatment of
periorbital wrinkles in the Indian population.

Keywords: Long pulsed Nd: YAG laser, Non ablative, Periorbital wrinkles, Skin resurfacing.


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